China Discount Price 38304-91-5 - L-Glutathione Oxidize 27025-41-8 Antioxidant – Neore manufacturers and suppliers

Discount Price 38304-91-5 - L-Glutathione Oxidize 27025-41-8 Antioxidant – Neore

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Discount Price 38304-91-5 - L-Glutathione Oxidize 27025-41-8 Antioxidant – Neore Detail:

Payment: T/T, L/C
Product Origin: China
Shipping Port: Beijing/Shanghai/Hangzhou
Order (MOQ): 1kg
Lead Time: 3 working days
Production capacity: 1000kg/month
Storage condition: Stored in cool, dry place, room temperature.
Package material: drum
Package size: 1kg/drum, 5kg/drum, 10kg/drum, 25kg/drum

L-Glutathione oxidize

Introduction

Glutathione can occur in reduced (GSH), oxidized (GSSG), or in mixed disulfide forms and is ubiquitous in multiple biological systems serving as the major thiol-disulfide redox buffer of the cell. Glutathione, Oxidized (GSSG) is the oxidized version of the naturally occurring and very important antioxidant glutathione (GSH). In vivo GSSG is reduced back to GSH via the NADPH-dependent enzyme glutathione reductase. The ratio of GSH to GSSG is often used to gauge the level of oxidative stress in cells, with higher concentrations of GSSG implying more oxidative stress, therefore beeing an important bioindicator of cellular health. GSSG functions as a hydrogen acceptor in the enzymatic determination of NADP+ and NADPH and can be a proximal donor in S-glutathionylation post translational modifications. GSSG, along with glutathione and S-nitrosoglutathione (GSNO), have been found to bind to the glutamate recognition site of the NMDA and AMPA receptors (via their γ-glutamyl moieties), and may be endogenous neuromodulators. GSSG can be used as substrate for enzymatically assaying glutathione reductase.

Specification (assay 98% up by HPLC)

Items	Standards
Appearance	White crystalline powder
Odor	Odorless to faint odor
Identification (IR)	Pass test
Identification (HPLC)	Pass test
State of solution	Colorless to yellowish clear
Specific rotation (at 25℃)	-103° to -93°
Heavy metal (As Pb), mg/kg	≤20
Moisture, %	≤6.0
Residue on ignition, %	≤0.5
Ethanol, %	≤0.05
Single unknown impurity	≤1
Total unknown impurity	≤2
Total unknown impurity	≤4
Total plate count, cfu/g	≤100
Assay, %	≥98.0

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