Factory directly Alpha-Arbutin - Posaconazole 171228-49-2 Antibiotic – Neore
Factory directly Alpha-Arbutin - Posaconazole 171228-49-2 Antibiotic – Neore Detail:
Payment: T/T, L/C
Product Origin: China
Shipping Port: Beijing/Shanghai/Hangzhou
Production capacity: 20kg/month
Order(MOQ): 10g
Lead Time: 3 Working Days
Storage condition: Stored in cool, dry place, room temperature.
Package material: vial
Package size: 10g/vial
Safety information: Not dangerous goods
Introduction
Posaconazole is a triazole antifungal medication.
Posaconazole is used to treat invasive Aspergillus and Candida infections. It is also used for the treatment of oropharyngeal candidiasis (OPC), including OPC refractory to itraconzaole and/or fluconazole therapy.
It is also used to treat invasive infections by Candida, Mucor, and Aspergillus species in severely immunocompromised patients.
Specification (in house standard)
|
Item |
Specification |
| Appearance | White or almost white, hygroscopic powder |
|
Item |
Specification |
|
Appearance |
White or off-white crystalline powder |
|
Specific rotation |
-28.0°~-34.0° |
|
Crystal form |
It should be crystalline Ⅰ, with 2-theta angles of 14.4±0.2°,19.2±0.2°,21.7±0.2°,24.3±0.2°29.3±0.2° |
|
Identification |
IR, HPLC |
|
Related substances I |
PO-R1 NMT 0.10% |
|
PO-R2 NMT 0.10% |
|
|
PO-R3 NMT 0.10% |
|
|
PO-R4 NMT 0.10% |
|
|
PO-D3 & PO-D5 NMT 0.10% |
|
|
PO-D7 & PO-D10 NMT 0.10% |
|
|
Each of unspecified impurity NMT 0.10% |
|
|
Total impurities NMT 0.5% |
|
|
Related substances Ⅱ |
PO-E NMT 0.10% |
|
PO-D1 NMT 0.10% |
|
|
PO-R5 NMT 0.10% |
|
|
Residual solvents |
Methanol NMT 3000ppm |
|
Ethanol NMT 5000ppm |
|
|
Dichloromethane NMT 600ppm |
|
|
Tetrahydrofuran NMT 720ppm |
|
|
N, N-dimethyl formamide NMT 880ppm |
|
|
Triethylamine NMT 100ppm |
|
|
Dimethy sulfoxide NMT 5000ppm |
|
|
Water |
NMT 2.0% |
|
Residue on ignition |
NMT 0.1% |
|
Heavy metals |
NMT 10ppm |
|
Microbial limit |
Total aerobic NMT 1000cfu/g Total yeasts and molds NMT 100cfu/g E.coli should be absent |
|
Assay |
98.0%-102.0%(on anhydrous basis) |
|
98.0%-102.0%(on anhydrous and solvents free basis) |
Product detail pictures:
Related Product Guide:
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By Marjorie from Comoros - 2017.09.26 12:12
