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Factory made hot-sale 497-76-7 - Sevoflurane 28523-86-6 General Anaesthetic – Neore

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Factory made hot-sale 497-76-7 - Sevoflurane 28523-86-6 General Anaesthetic – Neore Detail:

Payment: T/T, L/C
Product Origin: China
Shipping Port: Beijing/Shanghai/Hangzhou
Production capacity: 1500kg/month
Order(MOQ): 25kg
Lead Time: 3 Working Days
Storage condition: Stored in cool, dry place, room temperature.
Package material: drum
Package size: 25kg/drum
Safety information:  Not dangerous goods

Sevoflurane

Introduction

Sevoflurane is a sweet-smelling, nonflammable, highly fluorinated methyl isopropyl ether used as an inhalational anaesthetic for induction and maintenance of general anesthesia. After desflurane, it is the volatile anesthetic with the fastest onset. While its offset may be faster than agents other than desflurane in a few circumstances, its offset is more often similar to that of the much older agent isoflurane. While sevoflurane is only half as soluble as isoflurane in blood, the tissue blood partition coefficients of isoflurane and sevoflurane are quite similar.

Specification (R0-CEP 2016-297-Rev 00)

Item

Specification

Appearance

Clear, colourless, volatile liquid

Identification

IR spectrum of sample is consistent with that of reference standard.

Acidity or alkalinity

Colour reaction: ≤0.10mL of 0.01M sodium hydroxide or  ≤0.60mL of 0.01M hydrochloric acid.

Refractive index

1.2745 – 1.2760

Related substances

Impurity A:  ≤25ppm

Impurity B:  ≤100ppm

Impurity C:  ≤100ppm

Sevochlorance:  ≤60ppm

Any unspecified impurity:  ≤100ppm

Total impurities:  ≤300ppm

(Disregard any impurity less than 5ppm)

Fluorides

 ≤2μg/mL

Non-volatile residue

 ≤1.0mg per 10.0mL

Water

 ≤0.050%

Microbial limit

Total aerobic microbial limit: Not exceed 100CFU/mL

Total yeast and molds count: Not exceed 10CFU/mL

Bile-tolerant gram-negative bacteria: It is absent per mL

Staphylococcus aureus: It is absent per mL

Pseudomonas aeruginosa: It is absent per mL

Assay

Contains 99.97% – 100.00% of C4H3F7O


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