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Factory making 3-O-Ethyl Ascorbic Acid 86404-04-8 - Alprostadil 745-65-3 Hormone and endocrine – Neore

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Factory making 3-O-Ethyl Ascorbic Acid 86404-04-8 - Alprostadil 745-65-3 Hormone and endocrine – Neore Detail:

Payment: T/T, L/C
Product Origin: China
Shipping Port: Beijing/Shanghai/Hangzhou
Production capacity: 1kg/month
Order(MOQ): 1g
Lead Time: 3 Working Days
Storage condition: with ice bag for transportation, -20℃ for long term storage
Package material: vial, bottle
Package size: 1g/vial, 5/vial, 10g/vial, 50g/bottle, 500g/bottle
Safety information: UN 2811 6.1/PG 3

Alprostadil

Introduction

Alprostadil, also named Prostaglandin E1 or PEG1. It is widely present in the body of biologically active substances, as one of the prostaglandin family, it is a recognized endogenous physiologically active substance.

It can be used directly on vascular smooth muscle, to dilates blood vessels and increases blood flow, which can improve microcirculation perfusion. It can inhibit platelet aggregation and thromboxane A2 production, as well as inhibits atherosclerosis, lipid plaque and immune complex formation.

It also owns following effects: to expansion of the periphery small blood vessels and coronary arteries, reduction of peripheral vascular resistance and blood pressure. To protect platelet membrane which can against thrombosis. To protection the ischemic myocardium, which can reducing myocardial infarct size. It use to treat anti-heart failure as well. It has diuretic and renal-protecting function, base on expansion renal blood vessels in order to increase renal blood flow. During this way, it can remove non-protein nitrogen, and regulating sodium and water balance.

It’s clinically usage are widely. Such as for diabetic complications, coronary heart disease and intractable heart failure. Also usage on situation like congenital heart disease complicated with pulmonary hypertension, cerebral infarction and chronic arterial occlusive disease. For some cases like sudden deafness, retinal vein occlusion, viral hepatitis or chronic gastritis, it also have function. It can apply clinically on other disease like duodenal ulcer, chronic renal insufficiency and pancreatitis. It’s application in organ transplantation. Used for other disease such as erectile dysfunction, labor induction and postpartum hemorrhage, femoral head necrosis, lumbar disc herniation, postherpetic neuralgia and bronchial asthma.

It must caution use for patients who have disease like heart failure, glaucoma, peptic ulcer or interstitial pneumonia. With the irritant effect to vein, will show symptoms of inflammation such as redness, swelling, heat and pain, which may cause phlebitis. It must stop to use for safety when upon situation happen.

Specification (USP43)

Item

Specification

Appearance White or slightly yellowish crystalline powder
Identification IR
Residue on ignition ≤0.5%
Limit of chromium ≤0.002%
Limit of rhodium ≤0.002%
Related substances Prostaglandin A1 ≤1.5%
Prostaglandin B1 ≤0.1%
Any foreign prostaglandin impurity eluting before prostaglandin A1 ≤0.9%
Impurity at relative retention time 0.6, relative to prostaglandin A1 ≤0.9%
Sum of the impurities at relative retention times 2.0 and 2.3  ≤0.6%
Any other foreign prostaglandin impurity  eluting after prostaglandin A1 ≤0.9%
Total impurities ≤2.0%
Water determination ≤0.5%
Residual solvents Ethanol ≤5000ppm
Acetone ≤5000ppm
Dichloromethane ≤600ppm
N-Hexane ≤290ppm
N-Heptane ≤5000ppm
Ethyl acetate ≤5000ppm
Assay (on the anhydrous basis) 95.0%~105.0%

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Factory making 3-O-Ethyl Ascorbic Acid 86404-04-8 - Alprostadil 745-65-3 Hormone and endocrine – Neore detail pictures


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Excellent 1st,and Client Supreme is our guideline to deliver the ideal provider to our prospects.Nowadays, we have been seeking our best to become certainly one of the most effective exporters in our discipline to meet shoppers more require for Factory making 3-O-Ethyl Ascorbic Acid 86404-04-8 - Alprostadil 745-65-3 Hormone and endocrine – Neore , The product will supply to all over the world, such as: Madrid, Guyana, Leicester, We have been committed to meet all your needs and solve any technical problems you may encounter with your industrial components. Our exceptional products and vast knowledge of technology makes us the preferred choice for our customers.
  • We have been engaged in this industry for many years, we appreciate the work attitude and production capacity of the company, this is a reputable and professional manufacturer.
    5 Stars By Yannick Vergoz from Denmark - 2018.06.28 19:27
    It can be said that this is a best producer we encountered in China in this industry, we feel lucky to work with so excellent manufacturer.
    5 Stars By Gary from Nicaragua - 2017.11.20 15:58