High definition 28523-86-6 - Spironolactone 52-01-7 Urinary system – Neore
High definition 28523-86-6 - Spironolactone 52-01-7 Urinary system – Neore Detail:
Payment: T/T, L/C
Product Origin: China
Shipping Port: Beijing/Shanghai/Hangzhou
Production capacity: 50kg/month
Order(MOQ): 25kg
Lead Time: 3 Working Days
Storage condition: Stored in cool, dry place, room temperature.
Package material: drum
Package size: 25kg/drum
Safety information: Not dangerous goods
Introduction
Spironolactone, is a medication that is primarily used to treat fluid build-up due to heart failure, liver scarring, or kidney disease. It is also used in the treatment of high blood pressure, low blood potassium that does not improve with supplementation, early puberty in boys, acne and excessive hair growth in women, and as a part of transgender hormone therapy in transfeminine people.
Specification (USP42)
|
Item |
Specification |
|
Appearance |
Light cream-colored to light tan crystalline powder. |
|
Solubility (annual) |
Freely soluble in benzene and in chloroform; soluble in ethyl acetate and in alcohol; slightly soluble in methanol and in fiexed oils; practically insoluble in water. |
|
Identification |
Infrared Absorption: meets the requirement |
|
HPLC: meets the requirement |
|
|
Limit of mercapto compounds |
≤0.10mL of 0.010N iodine is consumed |
|
Organic impurities |
Related compound B ≤0.2% |
|
Related compound A ≤0.2% |
|
|
Related compound C ≤0.2% |
|
|
Related compound D ≤0.3% |
|
|
Epimer ≤0.3% |
|
|
Related compound I ≤0.1% |
|
|
Any unspecified impurity ≤0.10% |
|
|
Total impurities ≤1.0% |
|
| Optical rotation | -41°~ -45° |
| Loss on drying | ≤0.5% |
| Residual solvents (In-house) | Methanol ≤3000ppm |
| Tetrahydrofuran ≤720ppm | |
| DMF ≤880ppm | |
| Particle size (In-house) | 95% not more than 20 microns |
|
Assay |
97.0% ~103.0% on the dried basis |
Product detail pictures:
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By Deirdre from Indonesia - 2018.10.01 14:14
