China Hot New Products Alpha-Lipoic Acid 1077-28-7 - Diosmin-Hesperidin Mixture 90:10 – Neore manufacturers and suppliers

Hot New Products Alpha-Lipoic Acid 1077-28-7 - Diosmin-Hesperidin Mixture 90:10 – Neore

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Hot New Products Alpha-Lipoic Acid 1077-28-7 - Diosmin-Hesperidin Mixture 90:10 – Neore Detail:

Payment: T/T, L/C
Product Origin: China
Shipping Port: Beijing/Shanghai/Hangzhou
Production capacity: 1000kg/month
Order(MOQ): 25kg
Lead Time: 3 Working Days
Storage condition: Stored in cool and dry place, sealed and keep away from light.
Package material:drum
Package size:25kg/drum
Safety information: Not dangerous goods

Diosmin Hesperdin

Introduction

Diosmin is a semisynthetic flavonoid molecule derived from citrus d (modified hesperidin).
The product is used for treating various disorders of blood vessels including hemorrhoids, varicose veins, poor circulation in the legs (venous stasis), and bleeding (hemorrhage) in the eye or gums.
It is often taken in combination with hesperidin.

Hesperidin is a flavonoid found in the rinds of citrus fruits (such as oranges, lemons or pumelo fruits). The peel and membranous parts of these fruits have the highest hesperidin concentrations, especially in immature little citrus fruits. It is one of the flavonoids that give citrus fruits their color and taste.

The flavonoid hesperidin is a flavanone glycoside (glucoside) comprised of the flavanone (a class of flavonoids) hesperitin and the disaccharide rutinose. Flavonoids are a type of polyphenol, which are antioxidants found in plants and are essential to human health. Besides its antioxidant properties, hesperidincan also be used as an anti-inflammatory, anti-allergic, hypolipidemic, vasoprotective, and anti-carcinogenic compound. It seems to reduce the symptoms of allergies and hay fever by inhibiting histamine production in the blood.

Specification (in house)

Item

Specification

Appearance

Greyish-yellow or light yellow hygroscopic powder

Identification

HPLC: the principal peaks in the chromatogram obtained with the test solution is similar in retention time and size to the principal peak in the chromatogram obtained with reference solutions of diosmin and hesperidin respectively.

Tests- Iodine

- Water

- Heavy metals

- Sulfated ash

≤ 0.1%

≤ 6.0 %

≤ 20 ppm

≤ 0.2 %

Related Substances- Acetoisovanillone (impurity A)

- Isorhoifolin (impurity C)

- 6-iododiosmin (impurity D)

- Linarin (impurity E)

- Diosmetin (impurity F)

- Unspecified impurities, for each impurity

- Total

≤ 0.5%

≤ 3.0 %

≤ 0.6 %

≤ 3.0 %

≤ 2.0 %

≤ 0.4 %

≤ 8.5 %

ASSAY(HPLC), anhydrous substance- Diosmin

- Hesperidin

≥81.0%

≥9.0%

Particle Size

100% pass 80 mesh sieve

Residual Solvents- Methanol

- Ethanol

- Pyridine

≤ 3000 ppm

≤ 5000 ppm

≤ 200 ppm

Microbiological Tests- Total aerobic microbial count

- Total yeasts and moulds count

- Escherichia coli

- Salmonella Spp.

≤ 103 CFU/g

≤ 102 CFU/g

Absent in 1 g

Absent in 10 g

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