Hot New Products Ponazuril 69004-04-2 - Moxidectin 113507-06-5 Anti-Parasitics – Neore
Hot New Products Ponazuril 69004-04-2 - Moxidectin 113507-06-5 Anti-Parasitics – Neore Detail:
Payment: T/T, L/C
Product Origin: China
Shipping Port: Beijing/Shanghai/Hangzhou
Order (MOQ): 25kg
Lead Time: 3 working days
Production capacity: 100kg/month
Storage condition: Stored in cool, dry place, room temperature.
Package material: drum
Package size: 25kg/drum
Safety information: UN2811 6.1/PG 3
Introduction
Moxidectin is an anthelmintic drug used in animals to prevent or control parasitic worms (helminths), such as heartworm and intestinal worms, in dogs, cats, horses, cattle and sheep. Moxidectin kills some of the most common internal and external parasites by selectively binding to a parasite’s glutamate-gated chloride ion channels. These channels are vital to the function of invertebrate nerve and muscle cells; when moxidectin binds to the channels, it disrupts neurotransmission, resulting in paralysis and death of the parasite.
Specification (USP)
|
Item |
Specification |
| Appearance | White or pale yellow amorphous powder |
| Identification | IR Spectrum of sample corresponds to that of reference substance |
| The retention time of the major peak of the sample solution corresponds to that of the standard solution, as obtained in the assay | |
| Water | ≤1.3% |
| Residue on ignition | ≤0.2% |
| Heavy metals | ≤20ppm |
| Assay | 92.0-102.0% (anhydrous Substance) |
| Organic Impurities | |
| Early-eluting impurities | Moxidectin butenyl analog ≤1.5% |
| 5’-Demethyl Moxidectin ≤0.5% | |
| Moxidectin Pentenyl Analog ≤1.5% | |
| Moxidectin 17a-epimer ≤2.5% | |
| Sum of moxidectin 19-s-17a-ene and moxidectin ethyl isomers (E+F) ≤1.7% | |
| Mibemycin B analog (moxidectin open ring) ≤1.5% | |
| Any other individual impurity eluting before milbemycin B analog (moxidectin open ring) ≤0.5% | |
| Late Elutomg impurities | Moxidectin deoxydienea, and 4’-Methylthiomethoxymoxidectin (H+I) ≤ 1.0% |
| 20b-Methylthiomoxidctin (J) ≤ 0.5% | |
| 20-Nitrobenzoylmoxidectin (K) ≤ 0.5% | |
| Any other individual impurity eluting after the milbemycin B analog (Moxidectin open ring) ≤ 0.5% | |
| Total organic Impurities | ≤7.0% |
| Solvent residue | Methanol ≤ 3000ppm
Methylene Chloride ≤ 300ppm Isopropyl Acetate ≤ 5000ppm N-Heptane ≤ 5000ppm |
| BHT | 0.3%-0.6% |
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By Dale from Holland - 2018.06.26 19:27
