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Hot sale Ascorbyl Tetraisopalmitate - Atipamezole HCL 104075-48-1 Antipyretic-analgesic – Neore

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Hot sale Ascorbyl Tetraisopalmitate - Atipamezole HCL 104075-48-1 Antipyretic-analgesic – Neore Detail:

Payment: T/T, L/C
Product Origin: China
Shipping Port: Beijing/Shanghai/Hangzhou
Production capacity: 100kg/month
Order(MOQ): 25kg
Lead Time: 3 Working Days
Storage condition: Stored in cool, dry place, room temperature
Package material:drum
Package size:25kg/drum
Safety information:  Not dangerous goods

Atipamezole HCL

Introduction

Atipamezole hydrochloride, chemical name: 4-(2-ethyl-2-indan) imidazole hydrochloride. Atipamezole hydrochloride competitively inhibits alpha 2 adrenergic receptors, and is an effective α2 adrenergic receptor blocker, which selectively and competitively inhibits α2 adrenergic receptors.

Its pharmacological effects are to reduce sedation, lower blood pressure, increase heartbeat and respiratory rate, and reduce analgesic effects of α2-adrenoceptor blockers, which are mainly used in the recovery of anesthesia after surgery on animals.

Specification (in house standard)

Item

Specification

Appearance White solid
Identification IR
Identification of chlorides Comparable to stand
Melting point 211℃-215℃
Total impuities ≤ 0.1%
Individual impuity ≤0.05%
Loss on drying ≤0.05%2hrs at 105℃
Sulpated ash 0.05% max
Ph of standard solution 5-6
Solution(1% soltion in water) colorless
Total Heavy metals

(As Pb Cd Cr Ni)

≤20ppm
Residual solvents Acetone<5000ppm
Methylbenzene<890ppm
Thf<720ppm
Methanol<3000ppm
Dichloromethane<600ppm
Ethyl acetate<5000ppm
N-hexane<290ppm
Ethyl alcohol<5000ppm
Purity (HPLC) ≥99%

Specification Injection grade

Item

Specification

Appearance Yellow to orange powderodorless.
Identification IR, HPLC

Residue on ignition

≤0.5%

Related substances

At 303nm

Amphotericin A ≤2.0%

Individual unknown impurity ≤1.0%

At 383nm

Amphotericin X1 ≤4.0%

Individual unknown impurity ≤2.0%

Total impurities

≤15.0%

Residual solvents

Acetone ≤0.5%

Methanol ≤0.3%

Microbiological limit

Aerobic microbial count ≤1000cfu/g

Molds & yeasts ≤100cfu/g

Escherichia coli  Absent in 1g

Bacterial endotoxins

<1.0EU/mg

Assay

≥850 amphotericin B units/mg, calculated on the dried basis


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