China Leading Manufacturer for 745-65-3 - Rivaroxaban 366789-02-8 Blood system protect Antithrombosis – Neore manufacturers and suppliers

Leading Manufacturer for 745-65-3 - Rivaroxaban 366789-02-8 Blood system protect Antithrombosis – Neore

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Leading Manufacturer for 745-65-3 - Rivaroxaban 366789-02-8 Blood system protect Antithrombosis – Neore Detail:

Payment: T/T, L/C
Product Origin: China
Shipping Port: Beijing/Shanghai/Hangzhou
Production capacity: 200kg/month
Order(MOQ): 25kg
Lead Time: 3 Working Days
Storage condition: Stored in cool, dry place, room temperature.
Package material: drum
Package size: 25kg/drum
Safety information: Not dangerous goods

Rivaroxaban

Introduction

Rivaroxaban, is an anticoagulant medication (blood thinner). It use in adults with nonvalvular atrial fibrillation (except atrial fibrillation due to rheumatic valvular heart disease, and atrial fibrillation after heart valve replacement) to reduce the risk of stroke and systemic embolism.
Rivaroxaban, is used to treat and prevent blood clots.
Rivaroxaban, is used f for adult patients undergoing elective hip or knee replacement surgery to prevent venous thrombosis.

Specification (EP)

Item	Specification
Appearance	White or yellowish powder
Solubility	Practically insoluble in water, freely soluble in DMSO, practically insoluble in anhydrous ethanol and in heptanes.
Identification	IR: Spectrum should comply with the WS
	HPLC-RT of sample under enantiometric purity test should comply with that of WS.
Water	≤0.5%
Sulphate ash	≤0.1%
Loss on drying	≤0.5%
Heavy metals	≤20ppm
Enantionmer	Impurity A: ≤0.4%
Residual solvent	Ethanol: ≤5000ppm Ethyl acetate: ≤5000ppm Acetone: ≤5000ppm N,N-Dimethylformamide: ≤880ppm Methylene chloride: ≤600ppm Benzene: ≤2ppm
Related substance	Impurity B: ≤0.10% Impurity D: ≤0.10% Impurity E: ≤0.10% Impurity F: ≤0.10% Impurity G: ≤0.10% Impurity H: ≤0.10% Impurity I: ≤0.10% Impurity J: ≤0.10% RVB-4-NJSH: ≤0.10% RVB-ZA: ≤0.10% RVB-BAM: ≤0.10% RVB-ZC: ≤0.10% RVB-HBY: ≤75ppm Any other unknown impurity: ≤0.10% Total impurity: ≤0.3%
Particle size distribution	D10:/ D50:/ D90:/
Assay (anhydrous substance)	98.0-102.0

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