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Low price for 65896-14-2 - Mirabegron 223673-61-8 Inhibitor Neuronal signal – Neore

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Low price for 65896-14-2 - Mirabegron 223673-61-8 Inhibitor Neuronal signal – Neore Detail:

Payment: T/T, L/C
Product Origin: China
Shipping Port: Beijing/Shanghai/Hangzhou
Production capacity: 100kg/month
Order(MOQ): 25kg
Lead Time: 3 Working Days
Storage condition: Stored in cool, dry place, room temperature.
Package material: drum
Package size: 25kg/drum
Safety information:  Not dangerous goods

Mirabegron

Introduction

Mirabegron, is a beta-3 adrenergic receptor agonist, which stimulates the beta-3 adrenergic receptor and relaxes the detrusor smooth muscle, thereby increasing bladder capacity and is used to treat symptoms of overactive bladder (OAB), such as urge incontinence, urgency, and frequency.

Its benefits are similar to antimuscarinic medication such as solifenacin or tolterodine.

Specification (USP/EP)

Item

Specification

Appearance White to off white powder

Identification

IR, HPLC
Water content NMT 0.5%
Residue on ignition NMT 0.1%
Heavy metal NMT 20ppm
Palladium content NMT 20ppm
Optical isomer NTM 0.5%
Related substance Z-168*: NMT 0.15%
  SC03610*: NMT 0.15%
  Any other unknown impurity: NMT 0.10%
  Total impurity: NMT 0.5%
2-(2-aminothianzol-4-yl) acetic acid NMT 0.1%
Residual solvent Methanol: NMT 0.3%
  Ethyl acetate: NMT 0.5%
  THF: NMT 0.072%
  Benzene: NMT 0.0002%
  Toluene: NMT 0.089%
Assay 98.0% – 102.0%
PSD D (0.5): 10μm - 30μm
  D (0.9): 20μm - 80μm

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