New Arrival China Tadalafil 171596-29-5 - Tofacitinib citrate 540737-29-9 Rheumatoid arthritis Anticancer – Neore
New Arrival China Tadalafil 171596-29-5 - Tofacitinib citrate 540737-29-9 Rheumatoid arthritis Anticancer – Neore Detail:
Payment: T/T, L/C
Product Origin: China
Shipping Port: Beijing/Shanghai/Hangzhou
Production capacity: 100kg/month
Order(MOQ): 25kg
Lead Time: 3 Working Days
Storage condition: Stored in cool, dry place, room temperature.
Package material: drum
Package size: 25kg/drum
Safety information: Not dangerous goods
Introduction
Tofacitinib, is a medication used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis.
Tofacitinib citrate is used to treat adults with moderately to severely active rheumatoid arthritis who have had an inadequate response to, or who are intolerant of, methotrexate.
Tofacitinib citrate is indicated for the treatment of moderate to severe active rheumatoid arthritis (RA) in adults who have responded inadequately to, or who are intolerant to one or more disease-modifying antirheumatic drugs.
Specification (in house)
|
Item |
Specification |
|
Appearance |
White or off-white crystalline powder |
|
Identification |
IR, HPLC |
|
Water |
≤1.5% |
|
Related Substances |
TOFA 06 ≤0.15% |
|
Tofacitinib trans isomer ≤0.15% |
|
|
Tofacitinib dehydrogenated ≤0.15% |
|
|
Each unknown impurity ≤0.10% |
|
|
Total Impurities: ≤1.0% |
|
|
Residual Solvents |
Ethanol ≤5000ppm |
|
Benzene ≤2ppm |
|
|
Toluene ≤890ppm |
|
|
Chlroroethane ≤1000ppm |
|
|
N,N-Dimethylformamide ≤800ppm |
|
|
Palladium ≤10ppm |
|
|
Dichloromethane ≤600ppm |
|
|
Sulphated ash |
≤0.1% |
|
Heavy Metal |
≤10ppm |
|
Chrial HPLC |
3S, 4S tofacitinib ≤0.15% |
|
Assay (on anhydrous basis) 98.0-102.0% |
Product detail pictures:
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