China OEM/ODM Manufacturer 96829-58-2 - Spironolactone 52-01-7 Urinary system – Neore manufacturers and suppliers

OEM/ODM Manufacturer 96829-58-2 - Spironolactone 52-01-7 Urinary system – Neore

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OEM/ODM Manufacturer 96829-58-2 - Spironolactone 52-01-7 Urinary system – Neore Detail:

Payment: T/T, L/C
Product Origin: China
Shipping Port: Beijing/Shanghai/Hangzhou
Production capacity: 50kg/month
Order(MOQ): 25kg
Lead Time: 3 Working Days
Storage condition: Stored in cool, dry place, room temperature.
Package material: drum
Package size: 25kg/drum
Safety information: Not dangerous goods

Spironolactone

Introduction

Spironolactone, is a medication that is primarily used to treat fluid build-up due to heart failure, liver scarring, or kidney disease. It is also used in the treatment of high blood pressure, low blood potassium that does not improve with supplementation, early puberty in boys, acne and excessive hair growth in women, and as a part of transgender hormone therapy in transfeminine people.

Specification (USP42)

Item	Specification
Appearance	Light cream-colored to light tan crystalline powder.
Solubility (annual)	Freely soluble in benzene and in chloroform; soluble in ethyl acetate and in alcohol; slightly soluble in methanol and in fiexed oils; practically insoluble in water.
Identification	Infrared Absorption: meets the requirement
Identification	HPLC: meets the requirement
Limit of mercapto compounds	≤0.10mL of 0.010N iodine is consumed
Organic impurities	Related compound B ≤0.2%
	Related compound A ≤0.2%
	Related compound C ≤0.2%
	Related compound D ≤0.3%
	Epimer ≤0.3%
	Related compound I ≤0.1%
	Any unspecified impurity ≤0.10%
	Total impurities ≤1.0%
Optical rotation	-41°~ -45°
Loss on drying	≤0.5%
Residual solvents (In-house)	Methanol ≤3000ppm
	Tetrahydrofuran ≤720ppm
	DMF ≤880ppm
Particle size (In-house)	95% not more than 20 microns
Assay	97.0% ~103.0% on the dried basis

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