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Top Suppliers 86347-15-1 - Posaconazole 171228-49-2 Antibiotic – Neore

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Top Suppliers 86347-15-1 - Posaconazole 171228-49-2 Antibiotic – Neore Detail:

Payment: T/T, L/C
Product Origin: China
Shipping Port: Beijing/Shanghai/Hangzhou
Production capacity: 20kg/month
Order(MOQ): 10g
Lead Time: 3 Working Days
Storage condition: Stored in cool, dry place, room temperature.
Package material: vial
Package size: 10g/vial
Safety information:  Not dangerous goods

Posaconazole

Introduction

Posaconazole is a triazole antifungal medication.
Posaconazole is used to treat invasive Aspergillus and Candida infections. It is also used for the treatment of oropharyngeal candidiasis (OPC), including OPC refractory to itraconzaole and/or fluconazole therapy.
It is also used to treat invasive infections by Candida, Mucor, and Aspergillus species in severely immunocompromised patients.

Specification (in house standard)

Item

Specification

Appearance White or almost white, hygroscopic powder

Item

Specification

Appearance

White or off-white crystalline powder

Specific rotation

-28.0°~-34.0°

Crystal form

It should be crystalline Ⅰ, with 2-theta angles of

14.4±0.2°,19.2±0.2°,21.7±0.2°,24.3±0.2°29.3±0.2°

Identification

IR, HPLC

Related substances I

PO-R1 NMT 0.10%

PO-R2 NMT 0.10%

PO-R3 NMT 0.10%

PO-R4 NMT 0.10%

PO-D3 & PO-D5 NMT 0.10%

PO-D7 & PO-D10 NMT 0.10%

Each of unspecified impurity NMT 0.10%

Total impurities NMT 0.5%

Related substances Ⅱ

PO-E NMT 0.10%

PO-D1 NMT 0.10%

PO-R5 NMT 0.10%

Residual solvents

Methanol NMT 3000ppm

Ethanol NMT 5000ppm

Dichloromethane NMT 600ppm

Tetrahydrofuran NMT 720ppm

N, N-dimethyl formamide NMT 880ppm

Triethylamine NMT 100ppm

Dimethy sulfoxide NMT 5000ppm

Water

NMT 2.0%

Residue on ignition

NMT 0.1%

Heavy metals

NMT 10ppm

Microbial limit

Total aerobic NMT 1000cfu/g

Total yeasts and molds NMT 100cfu/g

E.coli should be absent

Assay

98.0%-102.0%(on anhydrous basis)

98.0%-102.0%(on anhydrous and solvents free basis)


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We believe in: Innovation is our soul and spirit. Top quality is our life. Purchaser need is our God for Top Suppliers 86347-15-1 - Posaconazole 171228-49-2 Antibiotic – Neore , The product will supply to all over the world, such as: Haiti, Bangalore, Costa Rica, Furthermore, all of our products are manufactured with advanced equipment and strict QC procedures in order to ensure high quality. If you are interested in any of our products, please don't hesitate to contact us. We will do our best to meet your needs.
  • We have been appreciated the Chinese manufacturing, this time also did not let us disappoint,good job!
    5 Stars By Hellyngton Sato from Brisbane - 2018.12.11 11:26
    Superb technology, perfect after-sales service and efficient work efficiency, we think this is our best choice.
    5 Stars By Heloise from Marseille - 2018.12.22 12:52