China Wholesale 109581-93-3 - Mitomycin C 50-07-7 Antibiotic Antineoplastic – Neore manufacturers and suppliers

Wholesale 109581-93-3 - Mitomycin C 50-07-7 Antibiotic Antineoplastic – Neore

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Wholesale 109581-93-3 - Mitomycin C 50-07-7 Antibiotic Antineoplastic – Neore Detail:

Payment: T/T, L/C
Product Origin: China
Shipping Port: Beijing/Shanghai/Hangzhou
Production capacity: 5kg/month
Order(MOQ): 10g
Lead Time: 3 Working Days
Storage condition: Stored in cool, dry place, room temperature.
Package material: vial
Package size: 10g/drum
Safety information: UN 2811 6.1/ PG 1

Mitomycin C

Description

Mitomycin C is a mitomycin that is used as a chemotherapeutic agent by virtue of its antitumour activity.

It is given intravenously to treat upper gastro-intestinal cancers (e.g. esophageal carcinoma), anal cancers, and breast cancers, as well as by bladder instillation for superficial bladder tumours.

Mitomycin C is used in cancers, particularly bladder cancers and intraperitoneal tumours.

Mitomycin C is used in eye surgery where mitomycin C 0.02% is applied topically to prevent scarring during glaucoma filtering surgery and to prevent haze after PRK or LASIK; mitomycin C has also been shown to reduce fibrosis in strabismus surgery.

Mitomycin C is used in esophageal and tracheal stenosis where application of mitomycin C onto the mucosa immediately following dilatation will decrease re-stenosis by decreasing the production of fibroblasts and scar tissue.

Specification (USP/EP)

Item	Specification
Appearance	Blue-violet, crystalline powder
Identification	IR: The IR spectrum of the sample corresponds to the spectrum of reference standard
	HPLC: The retention time of the major peak of the sample solution corresponds to that of the standard solution, as obtained in the Assay
pH	6.0~7.5
Water	Not more than 2.5%
Crystallinity	Should conforms
Related Substances
Albomitomycin C (EP Impurity D)	Not more than 0.5%
Mitomycin B (EP Impurity C)	Not more than 0.5%
Cinnamamide (EP Impurity A)	Not more than 0.5%
Mitomycin A (EP Impurity B)	Not more than 0.5%
Any Individual Unspecified Impurity	Not more than 0.5%
Total Impurities	Not more than 2.0%
Residual Solvents
Methanol	Not more than 3000 ppm
Methylene Chloride	Not more than 600 ppm
Ethyl Acetate	Not more than 5000 ppm
Bacterial Endotoxins	Not more than 10 EU/mg
Assay	Not less than 970 mg/g of Mitomycin

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