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Wholesale 109581-93-3 - Tofacitinib citrate 540737-29-9 Rheumatoid arthritis Anticancer – Neore Featured Image
  • Wholesale 109581-93-3 - Tofacitinib citrate 540737-29-9 Rheumatoid arthritis Anticancer – Neore

Wholesale 109581-93-3 - Tofacitinib citrate 540737-29-9 Rheumatoid arthritis Anticancer – Neore

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Wholesale 109581-93-3 - Tofacitinib citrate 540737-29-9 Rheumatoid arthritis Anticancer – Neore Detail:

Payment: T/T, L/C
Product Origin: China
Shipping Port: Beijing/Shanghai/Hangzhou
Production capacity: 100kg/month
Order(MOQ): 25kg
Lead Time: 3 Working Days
Storage condition: Stored in cool, dry place, room temperature.
Package material: drum
Package size: 25kg/drum
Safety information:  Not dangerous goods

Tofacitinib citrate

Introduction

Tofacitinib, is a medication used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis.

Tofacitinib citrate is used to treat adults with moderately to severely active rheumatoid arthritis who have had an inadequate response to, or who are intolerant of, methotrexate.

Tofacitinib citrate is indicated for the treatment of moderate to severe active rheumatoid arthritis (RA) in adults who have responded inadequately to, or who are intolerant to one or more disease-modifying antirheumatic drugs.

Specification (in house)

Item

Specification

Appearance

White or off-white crystalline powder

Identification

IR, HPLC

Water

≤1.5%

Related Substances

TOFA 06 ≤0.15%

Tofacitinib trans isomer ≤0.15%

Tofacitinib dehydrogenated ≤0.15%

Each unknown impurity ≤0.10%

Total Impurities: ≤1.0%

Residual Solvents

Ethanol ≤5000ppm

Benzene ≤2ppm

Toluene ≤890ppm

Chlroroethane ≤1000ppm

N,N-Dimethylformamide ≤800ppm

Palladium ≤10ppm

Dichloromethane ≤600ppm

Sulphated ash

≤0.1%

Heavy Metal

≤10ppm

Chrial HPLC

3S, 4S tofacitinib ≤0.15%

Assay (on anhydrous basis) 98.0-102.0%
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