China Wholesale 109581-93-3 - Tofacitinib citrate 540737-29-9 Rheumatoid arthritis Anticancer – Neore manufacturers and suppliers

Wholesale 109581-93-3 - Tofacitinib citrate 540737-29-9 Rheumatoid arthritis Anticancer – Neore

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Wholesale 109581-93-3 - Tofacitinib citrate 540737-29-9 Rheumatoid arthritis Anticancer – Neore Detail:

Payment: T/T, L/C
Product Origin: China
Shipping Port: Beijing/Shanghai/Hangzhou
Production capacity: 100kg/month
Order(MOQ): 25kg
Lead Time: 3 Working Days
Storage condition: Stored in cool, dry place, room temperature.
Package material: drum
Package size: 25kg/drum
Safety information: Not dangerous goods

Tofacitinib citrate

Introduction

Tofacitinib, is a medication used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis.

Tofacitinib citrate is used to treat adults with moderately to severely active rheumatoid arthritis who have had an inadequate response to, or who are intolerant of, methotrexate.

Tofacitinib citrate is indicated for the treatment of moderate to severe active rheumatoid arthritis (RA) in adults who have responded inadequately to, or who are intolerant to one or more disease-modifying antirheumatic drugs.

Specification (in house)

Item	Specification
Appearance	White or off-white crystalline powder
Identification	IR, HPLC
Water	≤1.5%
Related Substances	TOFA 06 ≤0.15%
	Tofacitinib trans isomer ≤0.15%
	Tofacitinib dehydrogenated ≤0.15%
	Each unknown impurity ≤0.10%
	Total Impurities: ≤1.0%
Residual Solvents	Ethanol ≤5000ppm
	Benzene ≤2ppm
	Toluene ≤890ppm
	Chlroroethane ≤1000ppm
	N,N-Dimethylformamide ≤800ppm
	Palladium ≤10ppm
	Dichloromethane ≤600ppm
Sulphated ash	≤0.1%
Heavy Metal	≤10ppm
Chrial HPLC	3S, 4S tofacitinib ≤0.15%
Chrial HPLC	Assay (on anhydrous basis) 98.0-102.0%

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109581-93-3