Wholesale Oxytocin 50-56-6 - Tulathromycin 217500-96-4 Antibiotic Antifungal – Neore
Wholesale Oxytocin 50-56-6 - Tulathromycin 217500-96-4 Antibiotic Antifungal – Neore Detail:
Payment: T/T, L/C
Product Origin: China
Shipping Port: Beijing/Shanghai/Hangzhou
Production capacity: 400kg/month
Order(MOQ): 25kg
Lead Time: 3 Working Days
Storage condition: Stored in cool, dry place, room temperature.
Package material: drum
Package size: 25kg/drum
Safety information: Not dangerous goods
Introduction
Tulathromycin, is a broad-spectrum antibacterial agent with antibacterial activity against some gram-positive and Gram-negative bacteria. It especially sensitive to pathogens of respiratory diseases in cattle and pigs, such as Actinobacillus pleuropneumoniae, Pasteurella haemolyticus, Pasteurella haemorrhagica, histophilus sleep (Haemophilus sleep), Mycoplasma pneumoniae, Haemophilus parasuis, Bordetella bronchiseptica, etc.
The pharmacokinetic characteristics of Tulathromycin are that after single dose administration, it is rapidly absorbed at the injection site, the effective blood concentration is maintained for a long time, the elimination is slow, the apparent distribution volume is large, the bioavailability is high, and the concentration in peripheral tissue is higher than that in plasma. Extensive tissue distribution and good cell permeability are important characteristics of Tulathromycin metabolism. Accumulation in immune cells is also an important feature of Tulathromycin.
Tulathromycin inhibits bacterial protein synthesis by blocking the bacterial peptide transfer process. Due to some important defects of erythromycin, people need another drug to instead of erythromycin urgently. Tulathromycin is a new kind of macrolide semi synthetic antibiotic for animals. It has many advantages, such as low dosage, one-time administration, low residue, animal specific and so on. It not only has the advantages of macrolide drugs, but also has an ultra long half-life which is superior to other macrolide antibiotics. Base on the advantage of maintain effective therapeutic concentration in the body for a long time, it can achieve better bacteriostasis and sterilization.
After extensive clinical application, tulathromycin has obvious therapeutic effect on respiratory diseases of cattle and pigs. Thanks for the excellent antibacterial activity of Tulathromycin like small dosage using, long half-life and one-time administration, it can be used widely.
Tulathromycin is stronger than the macrolides widely used in the market currently, such as tylosin, tilmicosin and florfenicol. Which has huge potential applications.
Attention to be paid that Tulathromycin is relatively safe, without carcinogenicity, teratogenicity and genotoxicity. It will not induce gene mutation, but may produce cardiotoxicity. Need to follow advise of veterinary.
Specification (In House Standard)
|
Item |
Specification |
| Appearance | White or almost white powder |
| Solubility | It is freely soluble in methanol, acetone, and methyl acetate, soluble in ethanol |
| Specific optical rotation | -22° to -26° |
| Identification |
HPLC: retention time of major peak in the chromatogram of the assay preparation corresponds to that in the chromatogram of the strandard preparation obtained as specified in the assay IR: IR spectrum is consistent with CRS |
| Water | ≤2.5% |
| Residue on ignition | ≤0.10% |
| Heavy metals | ≤20ppm |
| Related substance |
Total impurity ≤6.0% Individual impurity ≤3.0% |
| Bacterial endotoxin | < 2 EU |
| Assay (anhydrous substance) | 95%-103% |
| Residual solvent |
N-Heptane≤5000ppm Dichloromethane ≤600ppm |
| Assay | Content of C41H79N3O12: 95%-103% (On Anydrous substance) |
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By Jill from UAE - 2018.09.16 11:31
The quality of the products is very good, especially in the details, can be seen that the company work actively to satisfy customer's interest, a nice supplier.
By John from Italy - 2018.12.25 12:43
